{"id":206988,"date":"2022-02-18T15:36:30","date_gmt":"2022-02-18T18:36:30","guid":{"rendered":"https:\/\/eephcfmusp.org.br\/portal\/online\/?p=206988"},"modified":"2025-07-23T11:12:36","modified_gmt":"2025-07-23T14:12:36","slug":"sindrome-de-guillain-barre","status":"publish","type":"post","link":"https:\/\/hcxfmusp.org.br\/portal\/sindrome-de-guillain-barre\/","title":{"rendered":"Tudo sobre a S\u00edndrome de Guillain-Barr\u00e9"},"content":{"rendered":"

A<\/span> S\u00edndrome de Guillain-Barr\u00e9 (SGB)<\/b> \u00e9 uma condi\u00e7\u00e3o autoimune que afeta parte do sistema nervoso perif\u00e9rico. Com isso, o paciente tende a evoluir para uma fraqueza progressiva e pode apresentar sintomas de formigamento ou dorm\u00eancia nos membros.<\/span><\/span><\/p>\n

\u201cNa maioria dos casos, a autoimunidade \u00e9 desencadeada ap\u00f3s uma infec\u00e7\u00e3o (gastrointestinal ou respirat\u00f3ria), ou vacina\u00e7\u00e3o\u201d, explica o Dr. Guilherme Diogo da Silva, neurologista do Grupo de Neurologia de Emerg\u00eancia e do Grupo de Neuroinfec\u00e7\u00f5es do <\/span>HCFMUSP<\/span><\/a>.<\/span><\/span><\/p>\n

A condi\u00e7\u00e3o \u00e9 considerada rara. Por ano, s\u00e3o diagnosticados de 1 a 4 casos a cada 100 mil brasileiros – a maior incid\u00eancia \u00e9 entre pessoas de 20 a 40 anos de idade, de acordo com dados do <\/span>Minist\u00e9rio da Sa\u00fade<\/span><\/a>.\u00a0<\/span><\/span><\/p>\n

Como \u00e9 feito o diagn\u00f3stico de Guillain-Barr\u00e9?<\/strong><\/span><\/h2>\n

Geralmente \u00e9 feito ap\u00f3s a avalia\u00e7\u00e3o cl\u00ednica do paciente, exames de<\/span> eletroneuromiografia e l\u00edquor, e a exclus\u00e3o de outras causas.\u00a0 Segundo o Dr. Guilherme, a apresenta\u00e7\u00e3o cl\u00ednica t\u00edpica \u00e9 uma fraqueza bilateral progressiva, com redu\u00e7\u00e3o ou aboli\u00e7\u00e3o de reflexos. A eletroneuromiografia mostra altera\u00e7\u00f5es das condi\u00e7\u00f5es motoras e sensitivas, seja desmielinizante (que \u00e9 mais comum) ou axonal. J\u00e1 o l\u00edquor mostra a dissocia\u00e7\u00e3o proteino-citol\u00f3gica (prote\u00edna elevada com celularidade normal).\u00a0<\/span><\/span><\/p>\n

Al\u00e9m de ser uma condi\u00e7\u00e3o rara, a <\/span>S\u00edndrome de Guillain-Barr\u00e9 <\/b>pode apresentar particularidades em alguns pacientes, que podem dificultar o diagn\u00f3stico e at\u00e9 exigir uma nova avalia\u00e7\u00e3o. \u201cNa primeira semana, em cerca de 40% dos pacientes as altera\u00e7\u00f5es da eletroneuromiografia podem n\u00e3o ser suficientes para fechar os crit\u00e9rios da <\/span>S\u00edndrome de Guillain-Barr\u00e9. <\/b>Al\u00e9m disso, at\u00e9 50% dos pacientes podem apresentar o l\u00edquor sem a dissocia\u00e7\u00e3o prote\u00edna-citol\u00f3gica, e 15% t\u00eam celularidade entre 5-50 c\u00e9lulas\u201d, afirma.<\/span><\/span><\/p>\n

S\u00edndrome de Guillain-Barr\u00e9 e a Covid<\/b><\/span><\/h2>\n

Apesar do risco ser muito baixo, houve casos de pacientes com <\/span>manifesta\u00e7\u00f5es neurol\u00f3gicas<\/span><\/a> ap\u00f3s a infec\u00e7\u00e3o causada por Covid-19 – entre essas manifesta\u00e7\u00f5es, est\u00e1 a SGB.<\/span><\/span><\/p>\n

\u201cEm rela\u00e7\u00e3o ao risco ap\u00f3s a vacina\u00e7\u00e3o contra Covid-19, um trabalho que fiz com colegas do Hospital S\u00edrio-Liban\u00eas mostrou que, usando um registro nacional de efeitos colaterais da vacina americana, o risco era menor do que 1 a cada 1.000.000 (um milh\u00e3o) de doses. Ou seja, o benef\u00edcio da vacina \u00e9 muito maior em compara\u00e7\u00e3o com o risco da s\u00edndrome\u201d, conta o Dr. Guilherme Diogo da Silva.<\/span><\/p>\n

Guillain-Barr\u00e9 na emerg\u00eancia\u00a0<\/b><\/span><\/h2>\n

As complica\u00e7\u00f5es da <\/span>SGB<\/b> podem apresentar sintomas que afetam o sistema nervoso aut\u00f4nomo: taquicardia, altera\u00e7\u00f5es na press\u00e3o arterial, sudorese, altera\u00e7\u00e3o no funcionamento do intestino e bexiga e disfun\u00e7\u00e3o pulmonar.<\/span><\/span><\/p>\n

Com isso, o paciente pode precisar de atendimento da emerg\u00eancia m\u00e9dica e, consequentemente, tratamentos para as complica\u00e7\u00f5es de gravidade. \u201cO tratamento pode incluir monitoriza\u00e7\u00e3o card\u00edaca, medica\u00e7\u00f5es para al\u00edvio dos sintomas, fisioterapia precoce para fraqueza muscular e suporte psicol\u00f3gico\u201d, orienta o Dr. Guilherme.<\/span><\/p>\n

\u00c9 extremamente importante que o m\u00e9dico entenda que a <\/span>S\u00edndrome de Guillain-Barr\u00e9<\/b> \u00e9 considerada uma emerg\u00eancia neurol\u00f3gica, e que exige hospitaliza\u00e7\u00e3o imediata. Se o paciente tem os m\u00fasculos da face afetados, precisa de ventila\u00e7\u00e3o mec\u00e2nica, pois tende a ter insufici\u00eancia respirat\u00f3ria.<\/span><\/span><\/p>\n

\u201cEm geral, devemos orientar os pacientes que a doen\u00e7a tem um bom progn\u00f3stico. Cerca de 85% dos casos j\u00e1 conseguem andar sem apoio em 6 meses\u201d, conclui o Prof. Dr. Guilherme Diogo da Silva.\u00a0<\/span><\/p>\n

O curso de <\/span>Neurologia na Emerg\u00eancia<\/b><\/a> do HCX aborda a <\/span>SGB<\/b> e outras condi\u00e7\u00f5es neurol\u00f3gicas mais comuns encontradas durante o atendimento no pronto-socorro. Acesse o site do <\/span>HCX<\/span><\/a> e confira mais detalhes!<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

A S\u00edndrome de Guillain-Barr\u00e9 (SGB) \u00e9 uma condi\u00e7\u00e3o autoimune que afeta parte do sistema nervoso perif\u00e9rico. Com isso, o paciente tende a evoluir para uma fraqueza progressiva e pode apresentar sintomas de formigamento ou dorm\u00eancia nos membros. \u201cNa maioria dos casos, a autoimunidade \u00e9 desencadeada ap\u00f3s uma infec\u00e7\u00e3o (gastrointestinal ou respirat\u00f3ria), ou vacina\u00e7\u00e3o\u201d, explica o […]<\/p>\n","protected":false},"author":149398,"featured_media":390475,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[390],"tags":[688,342,828,436,829,344,387,830,790],"class_list":["post-206988","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-covid-19","tag-eep","tag-emergencia-medica","tag-escola-de-educacao-permanente","tag-guillain-barre","tag-hcfmusp","tag-hospital-das-clinicas","tag-neurologia-de-emergencia","tag-sindrome-de-guillain-barre"],"yoast_head":"\nO que \u00e9 s\u00edndrome de Guillain-Barr\u00e9?<\/title>\n<meta name=\"description\" content=\"A S\u00edndrome de Guillain-Barr\u00e9 (SGB) \u00e9 uma condi\u00e7\u00e3o autoimune que afeta parte do sistema nervoso perif\u00e9rico.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hcxfmusp.org.br\/portal\/sindrome-de-guillain-barre\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tudo sobre a S\u00edndrome de Guillain-Barr\u00e9\" \/>\n<meta property=\"og:description\" content=\"A S\u00edndrome de Guillain-Barr\u00e9 (SGB) \u00e9 uma condi\u00e7\u00e3o autoimune que afeta parte do sistema nervoso perif\u00e9rico.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/hcxfmusp.org.br\/portal\/sindrome-de-guillain-barre\/\" \/>\n<meta property=\"og:site_name\" content=\"HCX - 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